tag:blogger.com,1999:blog-19636934974176166.post1283236178594068734..comments2023-12-22T04:17:29.046-08:00Comments on Exceptionally Brash: MY OWN diabetes prevention programExceptionally Brashhttp://www.blogger.com/profile/13177479330600606059noreply@blogger.comBlogger25125tag:blogger.com,1999:blog-19636934974176166.post-33416039152540061232013-01-15T21:37:20.124-08:002013-01-15T21:37:20.124-08:00no, I think at the time I was taking Dr. Oz recomm...no, I think at the time I was taking Dr. Oz recommendations, just one cap a day.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-65126530751737661562013-01-15T18:22:54.599-08:002013-01-15T18:22:54.599-08:00Were you supplementing a lot of omega 3?Were you supplementing a lot of omega 3?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-53619812597721596142013-01-15T18:09:49.296-08:002013-01-15T18:09:49.296-08:00btw, do you know what could possibly explain why o...btw, do you know what could possibly explain why on day 2-3 of the traz and not eating, I got a nosebleed and a couple of cuts that wouldn't stop bleeding. Weirdest thing, and then left as quickly as it came on.<br />I'll tell you, it was a weird several weeks, but I didn't want to tell the doc everything, I wanted to lose more weight first. ha haExceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-7115370861170653412013-01-15T18:07:27.787-08:002013-01-15T18:07:27.787-08:00ha ha, not going to happen like that here. I hate...ha ha, not going to happen like that here. I hate those people :-)Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-29820203409908637752013-01-15T03:06:35.987-08:002013-01-15T03:06:35.987-08:00Well, check out Woo's posts on dopamine. She t...Well, check out Woo's posts on dopamine. She thinks l-dopa from a herb called mucuna pruriens. Also, you could try amino acid precursors to catecholamines like l-tyrosine and dl-phenylalanine. Careful if prone to anxiety/insomnia. Very stimulating. I can't hack very much of that stuff at all.<br /><br />One could also visit one's GP and say they are feeling a bit gloomy and unmotivated lately. When offered an SSRI, one could say one has heard bad things about them and that one's libido is low to begin with so no thanks. One could say that one would like a drug that will increase libido and help lose a bit of weight to which the doctor replies, ok here's Wellbutrin. The patient walks away from the consult with a norepinephrin and dopamine reuptake inhibitor.<br /><br />Speaking in generalities.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-67460830219294854292013-01-15T03:01:07.795-08:002013-01-15T03:01:07.795-08:00OK, I take back what I said. 12.5 mg of trazodone ...OK, I take back what I said. 12.5 mg of trazodone is nothing and likely did not cause any of that. Your symptoms like the 6 lb fluid loss, heart palps, anxiety, feeling like you're going to die were more likely due to sodium restriction (and resulting Mg and K depletion) which is one of those CW wisdom things so deeply ingrained in us but actually mortally dangerous on a VLC diet. There have been fatalities from sudden cardiac death secondary to electrolyte imbalances on LC diets. I do remember a decade ago at the heyday of the Atkins diet reports appearing in the British newspapers about teenage girls dropping dead in the middle of the school day, stuff like that. Probably underlying undiagnosed conditions but still. The problem is that medicine is clueless about the nature of a healthy diet and NOBODY - and I mean nobody - warns you when you start dieting to supplement everything and you are even told, idiotically, that as part of a healthy diet you should cut salt. Yes, if you are really unlucky, you might end up in v fib as a result and die.<br /><br />It is good that you believed at the time that it was trazodone causing your symptoms but it's time to let go now. ;)<br /><br />Yes, I can see how taking DHEA and progesterone would make you feel and look, well, crap. Personally, I don't take any hormones but I do accept that the situation is very different post-menopause.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-40028495751701323972013-01-14T16:13:14.860-08:002013-01-14T16:13:14.860-08:00how do you raise dopaminergic tone w/o a prescript...how do you raise dopaminergic tone w/o a prescription? It is very easy to get stuff prescribed here off-label, as long as you don't have an HMO. I think those that got it did so because they were able to convince their docs that they had tried lots of other things to lower bg's that didn't work. I know Kruse was working on a way to do it w/o a prescription.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-71922797211638287322013-01-14T16:07:11.435-08:002013-01-14T16:07:11.435-08:00My take on Kruse's whole dopamine issue is tha...My take on Kruse's whole dopamine issue is that the risk-taking is necessary for survival during evolutionary change that can happen in step-fashion. Survival goes towards those that can change quickly. But, I don't see us changing all that quickly these days (maybe we'll need it later). It is one thing to be bold, it is another thing to continue to want to do the stupid things that filled our youth. It's great to go all Jim Morrison and break on through to the other side, but it didn't work so well for him, did it?Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-67146771149796935192013-01-14T16:02:03.266-08:002013-01-14T16:02:03.266-08:00Do you make a distinction between cryotherapy at t...Do you make a distinction between cryotherapy at the docs office and Woo's surgery? Kruse says don't try metal cryotherapy at home, but I think he gave insufficient evidence that the cold tubs do it. That said, there is nothing better for getting back into ketosis after a few days of eating badly than a day at the beach or in the cold tub. If you can get bg's down and then also get a wonderful night's sleep, I don't see a downside to doing it, except that it is not permanent.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-85884813853018210202013-01-14T15:46:23.922-08:002013-01-14T15:46:23.922-08:00....but I didn't get a very good night's s.......but I didn't get a very good night's sleep....did I?.... I was taking only 12.5 mg, half of the sleep dose, and from what I have read that shouldn't be enough for depression. Since my experience with traz, I have experienced some of the same hormonal changes (eg. get-up-and-go, libido, etc.) when starting DHEA, cold thermogenesis and progesterone, although not as pronounced. Trouble is, taking too much DHEA or progesterone or with too many carbs when overboard into skin problems and pms-like symptoms. I haven't gone overboard on CT yet to see what it will do.<br />Honestly, I never would have continued on my low carb journey if I had thought for a minute that all my weird symptoms weren't due to the trazodone. Many of the initial symptoms are the same as going on a low carb diet. It was a tough couple of weeks for sure, and only endurable because I was losing so much weight. I can't believe that at the time, I was still monitoring my SALT intake!Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-43951795497182351392013-01-14T15:39:03.484-08:002013-01-14T15:39:03.484-08:00Yeah that's bromocriptine quick release.Yeah that's bromocriptine quick release.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-62463788672819208772013-01-14T15:37:23.132-08:002013-01-14T15:37:23.132-08:00Oh, its cycloset. Here's another blogpost abo...Oh, its cycloset. Here's another blogpost about it.<br />http://sunvalleysoul.blogspot.com/2012/11/hormones-fasting-blood-glucose-and-ct.htmlExceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-72697470320142157032013-01-14T11:04:20.651-08:002013-01-14T11:04:20.651-08:00Trazodone is not just a sleeping pill, it is an an...Trazodone is not just a sleeping pill, it is an antidepressant accounting for your improved libido, energy and diminished interest in food. It doesn't act on dopamine but most antidepressants don't anyway. Perhaps you felt great after one dose because you got the first night of good sleep in ages. Other issues you describe like orthostatic hypotension, anxiety, tachycardia - they are very common side effects of this drug especially at the start.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-23693597399212653022013-01-14T10:55:31.845-08:002013-01-14T10:55:31.845-08:00It must be bromocriptine they're taking. It...It must be bromocriptine they're taking. It's a dopamine agonist that reduces HbA1c slightly and raises the dopaminergic tone which is low in obesity and post-obesity. How the hell do they get their docs to prescribe it off-label? I don't read Kruse but I arrived at the same conclusion independently that you need to raise the dopaminergic tone if you are to fight off the post-weight loss blues and blahs. I tried to convince someone usually quite open-minded to prescribe it and he wouldn't even entertain the discussion.<br /><br /><i>To me, this was disappointing because I was led to believe that he did have the answer to permanent weight loss.</i><br /><br />Brash, neither Jack Kruse nor anyone else in the world has the answer to permanent weight loss because no such answer exists. Kruse can't give you leptin replacement to trick the hypothalamus into thinking you didn't lose weight nor can he induce excess adipose tissue apoptosis which would be the only true permanent solution. He can lie and scam people all he wants but as you said, it's all experimental and you can see he's clearly making this stuff up as he goes along. It's nonsense. Sitting in cold baths and eating seafood all day long is not going to fix obesity which is actually an intractable problem which requires lifelong vigilance to prevent relapse.<br /><br /><i>while I am not an expert by any means, it seems to me that he is already on the high side for dopamine.</i><br /><br />Couldn't agree more. Maybe experimenting with self-prescribed dopamine agonists explains his behaviour in part?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-28575562831611803992013-01-14T08:29:04.671-08:002013-01-14T08:29:04.671-08:00BTW, can you perhaps tell me why I was lazy and mi...BTW, can you perhaps tell me why I was lazy and miserable for months on a lower-calorie, lower-salt, sugar-free diet and after one dose of trazodone, I woke up feeling wonderful, jumped out of bed, went for an early walk, had all my week's action items done by lunch? I lost 6 lb of water weight in a couple of days, and was dizzy lots of the time. Food, especially carbs, made me sick when I thought of eating. I forced food down for a few days, and then started craving proteins and fat. Later in the week I woke up at night a couple of times with my heart racing and thinking I was going to die. Then it was a couple of months of hyper-sexuality and weight loss. It couldn't be just from one good night of sleep. My sleep didn't really improve all that much for the first several weeks. IDN, sounds like dopamine to me, but stuff on the internet says traz will make you gain weight. And maybe getting into deep and uncomfortable ketosis at night? A rearrangement of all the hormones? Eventually weight loss stalled and everything went back to normal. I want to find out what happened and do it again for "the last 20"Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-58493091366445909962013-01-14T08:19:06.169-08:002013-01-14T08:19:06.169-08:00But, I need to qualify before the Kruse-h8trs mis-...But, I need to qualify before the Kruse-h8trs mis-quote me on some drama website, I do think many of his public suggestions have been very helpful for me and I am grateful for Kruse being in the diet territory here to help many of us.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-74284377459540620502013-01-14T08:17:20.024-08:002013-01-14T08:17:20.024-08:00My other "concern" if you will, is sort ...My other "concern" if you will, is sort of like on Beverly Hillbillies. In one episode, Granny insisted that she had the cure for the cold. She made Mr. Drysdale, I think, go through all sorts of mountain medicine cures, and drink nasty stuff, and at the end says, "Yep, a CURE for the cold! You'll start to feel better in a WEEK TO TEN DAYS!!!!" (This is an epic episode on this side of the pond. Too bad I couldn't find the link.) Likewise, Kruse will have you sitting in the cold and dark swilling raw oysters and in the end maybe it all boils down to getting the same treatment effect as a street drug or a drugstore diet pill.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-50576507939178131672013-01-14T08:12:35.919-08:002013-01-14T08:12:35.919-08:00Oh, I'll have to look it up somewhere. It is ...Oh, I'll have to look it up somewhere. It is something they are taking in the am, but I may be confusing it with another drug that they were taking to reduce blood sugar. It may be the same drug. To me, this was disappointing because I was led to believe that he did have the answer to permanent weight loss. It did not work that way for me, and for others, and I believe that he is continuing to experiment with stuff that will make the weight loss permanent. I do he is extremely interested in the whole dopamine issue, and while I am not an expert by any means, it seems to me that he is already on the high side for dopamine.<br />My concern is that as a public health strategy, Kruse's program doesn't work. That is, if the entire obese and overweight population does not have access to expensive webinars, non-standard and expensive testing, and off-label uses of controversial drugs, it can't be implemented. I already know my HMO won't prescribe such things. Sheesh, I can't even get them to order testing for my progesterone and estrogen levels! So, Kruse's program reads "epic-fail" for everyone but the elite, like the Life Extension folks.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-33527278397237104992013-01-12T09:32:56.752-08:002013-01-12T09:32:56.752-08:00EB, what dopaminergics are they taking do you know...EB, what dopaminergics are they taking do you know? Why does this concern you? Yes those drugs have potential dangers but so does everything. Woo and I and a few others have been experimenting with l-dopa.<br /><br />I have come to accept that a low dopaminergic tone is perhaps THE problem in weight loss maintenance. I have no idea what Kruse has said about this as I don't read anything he writes but I think he's right about dopamine being an issue. I say this solely on the basis of my own N=1 symptom watching and reading the literature.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-76414597190516030632013-01-12T08:00:22.584-08:002013-01-12T08:00:22.584-08:00While I was disappointed that the leptin reset/ct ...While I was disappointed that the leptin reset/ct protocol doesn't guarantee a permanent fix, I do feel that while doing it, I am slowly getting better and better. But you can tell by some of Kruse's posts and personal experiments that he hasn't found the holy grail of permanent weight loss. And it concerned me when many of the webinarians started taking a dopamine-enhancing drug. I know Kruse is tinkering to try to increase dopamine. I'll patiently wait by the sidelines until all their N=1's come in, thank you. The trouble with the paleo community kicking out Kruse is that all the other N=1's walled themselves in, and you almost never hear about the people who don't do well on it. Same as you never hear within the paleo community about the people who don't do well. This is sad for the state of knowledge in general, and will put them in the "fad fringe" category permanently, I feel.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-68435918656728776272013-01-12T07:53:54.812-08:002013-01-12T07:53:54.812-08:00@F, I would have probably been in that category as...@F, I would have probably been in that category as well, if I hadn't stuck with it and tried the Kruse protocols. I lost weight rapidly, but by a few months I felt like crap and was depleted from overexercising. I got a cold that lingered for a month. Afterwards, I could not get back on track. I struggled with Scharzbein for a month, then switched to Rosedale and lost most of the rest of my weight. It took me about 6 months to lose the rest of the weight. Then I went into "maintenance". As soon as I added in some carbs my weight shot up. (And from the plots, it looks like that is the same thing that happened with Gardner's study.) I developed my own strategies for getting myself back into ketosis. Then I started the leptin reset in earnest. I gave up exercise, got more sun, minimized heat-stress and took supplements to fix my adrenals. In the fall I started taking vitamin D. The next spring I started in with cold thermogenesis and started tinkering with a bit of hormone therapy, and I also paid attention to light cycles more than before.Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-81201812583966784292013-01-11T18:06:03.499-08:002013-01-11T18:06:03.499-08:00What I mean by outlier, is that standard dietary a...What I mean by outlier, is that standard dietary advice (even looking at a decent study like Gardner's A-to-Z) has an effectiveness of about 5-6 months, with most people trending back up after that and a success rate of 1% (if you want to look at meaningful weight loss at one year) and people who stick with an effective plan that works over the long term are the exception. <br /><br />They are outliers, with results not based on randomness. Plans based on science that actually works can put people in the outlier category. <br /><br />I admire the people who have the stick-to-it-iveness to seek out that science. <br /><br />Who doesn't want to be in the middle-aged EPIC group with a great chance of being alive in 6 years versus a sketchy chance of being alive? franklinhttps://www.blogger.com/profile/09611021623864239582noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-60536283194432388842013-01-11T16:38:16.166-08:002013-01-11T16:38:16.166-08:00here it is!!!
http://high-fat-nutrition.blogspot.c...here it is!!!<br />http://high-fat-nutrition.blogspot.com/search/label/EPIC%20HbA1c%20and%20heart%20attacks<br />An epic post indeedExceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-58333834379051291972013-01-11T16:22:02.056-08:002013-01-11T16:22:02.056-08:00Franklin, I don't believe I am an outlier. I ...Franklin, I don't believe I am an outlier. I think that I am just someone who won't quit, and I keep trying to make things better above and beyond tinkering with macronutrient ratios, and I am vocal. I do not think I am a special snowflake, I think that unfortunately, I am the norm for women my age. And, it pisses me off so much that everyone is ignoring this, that I just keep wanting to get louder and louder.<br />THIS study showed that people can keep it off, at least for a few years, but the problem is that they compare only to metformin and standard SAD-with-a-lecture, not to a low carb diet. Dr. Gardner showed that those wonderful group C women tending towards metabolic syndrome do much better on low carb. Why can't he get this published???? Why won't anybody pay attention to this?????<br />I'm going over to the-Hype right now to find that article. Dr. D has been the first health blog I have followed, and always my favorite.<br />BTW, my HbA1c went from 5.8 to 5.4 after a year on lower carb. ding ding ding ding!!!!!Exceptionally Brashhttps://www.blogger.com/profile/13177479330600606059noreply@blogger.comtag:blogger.com,1999:blog-19636934974176166.post-58274926507195951712013-01-11T15:55:57.893-08:002013-01-11T15:55:57.893-08:00EB-
All the studies show that the person who lose...EB-<br /><br />All the studies show that the person who loses meaningful weight and keeps it off for more than a year is a statistical outlier. My goal is to be an extreme statistical outlier.<br /><br />I think you are very smart to focus on HbA1C as a meaningful marker. Read Hyperlipid's post on "Sweet Heart Disease" discussing the EPIC trial and the death rates of middle-aged people at different HbA1C levels. It is in my top 5 of inspiring writings on diet and nutrition.<br /><br /> franklinhttps://www.blogger.com/profile/09611021623864239582noreply@blogger.com